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Những điều cần biết về thuốc dạ dày Kagasdine (omeprazol)

Kagasdine: An In-Depth Look at the Omeprazole Stomach Medicine

Kagasdine (omeprazole) is a medication widely used for various conditions. In this article, we will explore what Kagasdine is, its uses, possible side effects, and other important information about this medication. So, let’s dive in!

Kagasdine: What is it?

Kagasdine contains omeprazole as its active ingredient. Omeprazole belongs to the benzimidazole class and works by inhibiting the secretion of stomach acid. It does this by blocking the proton pump in the stomach lining cells, which is responsible for producing stomach acid. Kagasdine can also help eliminate the Helicobacter pylori bacteria that cause conditions like gastric ulcers and gastroesophageal reflux disease.

Thuốc Kagasdine
Image: Kagasdine (omeprazole) medicine

How much does Kagasdine cost?

Kagasdine is available in capsule form and comes in a pack of 2 blister packs, each containing 10 capsules. The price of Kagasdine 20mg is approximately 15,000 VND per pack. Please note that prices may vary depending on the supplier.

What can Kagasdine treat?

Kagasdine is prescribed for the following conditions:

  • Conditions with increased stomach acid secretion
  • Gastroesophageal reflux disease (GERD)
  • Gastric and duodenal ulcers
  • Zollinger-Ellison syndrome
  • Stress ulcers and non-steroidal anti-inflammatory drug-induced ulcers prevention

Precautions and Proper Usage of Kagasdine

Before using Kagasdine, it is important to be aware of certain precautions:

  • Do not use Kagasdine if you are allergic to omeprazole or any of the other ingredients in the medication.
  • Swallow the Kagasdine capsule whole, without crushing or chewing it.
  • Take Kagasdine on an empty stomach, preferably one hour before meals.

Dosage

The dosage of Kagasdine varies depending on the condition being treated:

  • To reduce acid-related digestive problems: Take 10-20mg of omeprazole daily for 2-4 weeks.
  • For the treatment of GERD: Take 20mg of omeprazole per dose for 4 weeks. If symptoms persist, continue the treatment for an additional 4-8 weeks.
  • For gastric and duodenal ulcers: Take 20-40mg of omeprazole daily. Treatment duration for gastric ulcers is 8 weeks, while for duodenal ulcers, it is 4 weeks.
  • For the eradication of H. pylori in gastric and duodenal ulcers: Combination therapy with omeprazole and antibiotics is recommended. The typical regimen includes 20mg of omeprazole twice daily, along with amoxicillin 1g and clarithromycin 500mg, both taken twice daily.

Please note that the dosage of Kagasdine mentioned here is for reference purposes only. Always follow the instructions provided by your doctor and do not adjust the dosage without medical guidance.

Possible Side Effects of Kagasdine

Kagasdine may cause the following side effects:

  • Headache, drowsiness, dizziness
  • Diarrhea, nausea, vomiting, abdominal pain, constipation
  • Insomnia, sensory disturbances, fatigue
  • Itching, rash
  • Temporary increase in liver enzymes
  • Sweating, peripheral edema, hypersensitivity reactions
  • Decreased white blood cells, decreased platelets, decreased overall blood cells, agranulocytosis
  • Confusion, agitation, depression, hallucinations (especially in elderly patients), hearing impairment
  • Breast enlargement in males
  • Gastritis, Candida infection, dry mouth
  • Liver inflammation with or without jaundice, hepatocellular injury in patients with liver impairment
  • Bronchospasm
  • Joint pain, muscle pain
  • Interstitial nephritis
  • Additionally, proton pump inhibitors may increase the risk of gastrointestinal infections such as Salmonella and Campylobacter due to reduced gastric acid secretion.

Tác dụng phụ của thuốc Kagasdine có thể gây chóng mặt buồn ngủ
Image: Possible side effects of Kagasdine: dizziness and drowsiness

Interactions with Other Drugs

Kagasdine may interact with the following medications:

  • Ciclosporin
  • Diazepam
  • Phenytoin
  • Warfarin
  • Dicoumarol
  • Nifedipine
  • Clarithromycin

Special Precautions for Specific Groups

Pregnant Women

Studies on animals have not shown any teratogenic or harmful effects of omeprazole on fetal development. However, more research is needed to determine its safety for pregnant women. Therefore, it is important to consult with a healthcare professional before using Kagasdine during pregnancy.

Breastfeeding Women

Omeprazole is excreted into breast milk. Therefore, it is advisable to consider discontinuing the medication or stop breastfeeding while using Kagasdine.

Driving and Operating Machinery

Kagasdine may cause central nervous system side effects such as drowsiness, headache, and dizziness. Therefore, caution should be exercised when driving or operating machinery to ensure safety.

Overdose and Missed Dose of Kagasdine

In case of an overdose, where doses of up to 160mg per intake, 80mg per day for intravenous injection, or 520mg over 3 days have been reported, patients primarily experience drowsiness, headache, and increased heart rate. However, in reported cases, patients recovered without any additional treatment.

If a dose of Kagasdine is missed:

  • Take the missed dose as soon as you remember.
  • If the missed dose is close to the next dose, skip the missed dose and continue with the regular dosing schedule.
  • Do not double the dose to make up for the missed dose.

Storage of Kagasdine

  • Keep Kagasdine out of reach of children and pets.
  • Store the medication in a cool, dry place, away from direct sunlight or moisture.
  • The ideal storage temperature is below 30 ºC.

The information presented here covers the usage of Kagasdine in treating acid-related digestive problems, GERD, ulcers, and more. If you experience any unusual symptoms, be sure to contact your doctor for proper evaluation and timely support!


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